Electronic ISSN 2287-0237

VOLUME

WHAT HAVE WE LEARNED FROM THE PAST 7 YEARS AND THE MILLIONS OF DOLLARS SPENT ON THE GENOME-WIDE ASSOCIATION STUDIES?

FEBRUARY 2014 - VOL.7 | OTHER FEATURE
  1. Hindorff LA, MacArthur J (European Bioinformatics Institute), Morales J (European Bioinformatics Institute), Junkins HA, Hall PN, Klemm AK, and Manolio TA. A Catalog of Published Genome-Wide Association Studies. (Accessed December 22, 2013, at: www.genome.gov/ gwastudies).
  2. Nuinoon M, Makarasara W, Mushiroda T, et al. A genome- wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemo- globin E. Hum Genet 2010;127:303-14.
  3. Mahasirimongkol S, Yanai H, Mushiroda T, et al. Genome- wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis J Hum Genet 2012;57:363-7.
  4. Kamatani Y, Wattanapokayakit S, Ochi H, et al. A genome- wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians. Nat Genet  2009;41:591-5.
  5. Nishida N, Sawai H, Matsuura K, et al. Genome-wide study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean. PLoS One 2012;7:e39175.
  6. Yang W, Shen N, Ye DQ, et al. Genome-wide association study in Asian populations identifies variants in ETS1 andWDFY4associatedwithsystemiclupuserythematosus. PLoS Genet 2010;6:e1000841.
  7. Jongjaroenprasert W, Phusantisampan T, Mahasirimongkol S, et al. A genome-wide association study identifies novel susceptibility geneticvariationforthyrotoxichypokalemic periodic paralysis. J Hum Genet 2012;57:301-4.
  8. Chantarangsu S, Mushiroda T, Mahasirimongkol S, et al. Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash. Clin Infect Dis 2011;53:341-8.
  9. Manolio TA. Bringing genome-wide association findings into clinical use. Nat Rev Genet 2013;14: 549-58.
  10. Sanna S, Li B, Mulas A, et al. Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. PLoS Genet 2011;7: e1002198.
  11. Palomaki GE, Melillo S, Bradley LA. Association between 9p21 genomic markers and heart disease: a meta-analysis. JAMA 2010; 303:648-56.
  12. Database of Single Nucleotide Polymorphisms (dbSNP). Bethesda (MD): National Center for Biotechnology Information, National Library of Medicine. (dbSNP Build ID: 139). (Accessed December 25, 2013, at http://www. ncbi.nlm.nih.gov/SNP/).
  13. Maher B. Personal genomics: the case of the missing heritability. Nature 2008;456:18-21.
  14. Van der Net JB, Janssens AC, Sijbrands EJ, et al. Value of genetic profiling for the prediction of coronary heart disease. Am Heart J 2009;158:105-10.
  15. Cirulli ET and Goldstein DB. Uncovering the roles of rare variants in common disease through whole genome sequencing. Nature Rev Genet 2011;11:415-25.
  16. Mardis ER. The $1000 genome, the $100,000 analysis? Genome Medicine 2010; 2: 84.
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