Electronic ISSN 2287-0237

VOLUME

ORAL MALIGNANT MELANOMA OF THE MAXILLA: A CASE REPORT

FEBRUARY 2015 - VOL.9 | CASE REPORT

A case report of oral malignant melanoma (OMM). An 84-year-old male patient presented with enlarged, swollen anterior left upper gingiva with mild pain lasting eight weeks from the lower occluded teeth. Histopathological examination and immunohistochemical studies confirm OMM.

OBJECTIVES:

OMM, a neoplasm of melanocytes, is a rare aggressive tumor of the oral cavity. This paper aims to explain and discuss the clinical features, histopathology and immunohistochemical studies of OMM.

MATERIAL AND METHODS:

We report on a case of OMM treated at our institute. An oral examination, differential diagnosis and biopsy were performed for a definitive diagnosis. 

RESULTS:

Histopathological examination showed sheets of atypical melanocytic tumor cells with abundant cytoplasmic pigmentation. The tumor cells were positive for S-100 protein, HMB-45 and MART 1 or Melan A. A final diagnosis of OMM was made. 

CONCLUSION:

OMM is a rare tumor of the oral cavity with a poor prognosis; although an aggressive treatment is available to patients. Early diagnosis and aggressive multimodal treatment are important ways for surgeons to achieve a better outcome for patients with OMM.

Keywords:

oral malignant melanoma, maxilla, histopathology, immunohistochemistry

MEDIA
Figure 1:
Intraoral examination
Figure 2:
Histopathology
Figure 3:
Immunohistochemistry study
Figure 4:
Two months follow-up. Swollen palate and lesion extending to the left molar area with an increased hyperpigmentation.
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