Electronic ISSN 2287-0237

VOLUME

ADULT ONSET IMMUNODEFICIENCY ASSOCIATED WITH ANTI-INTERFERON GAMMA AUTOANTIBODIES

FEBRUARY 2017 - VOL.13 | REVIEWS ARTICLE

Adult onset immunodeficiency associated with anti-interferon-gamma autoantibodies is an emerging medical issue worldwide especially in South-east Asia. Most patients present with disseminated non-tuberculous mycobacteria (NTM) infection and other opportunistic infections. In addition to standard antimicrobial therapy, immunomodulator or immunosuppressive drug seem to play a role in some cases. In the present study, we thoroughly reviewed the pathogenesis, clinical features, laboratory diagnosis, modalities of treatment, and clinical outcomes of this condition.

MEDIA
Figure 1
Pathogenesis of interferon gamma autoantibody associated with adult onset immunodeficiency syndrome and role of Ritux imab in treatment
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